Our lab develops open-source software and packages to answer scientific questions:
In Silico Cytotoxicity Assessment
An innovative kinetic simulation framework developed to capture and evaluate the temporal and dose-dependent effects of chemical exposure. By reading cell impedance dynamics, Toxfit computes precise 50% inhibitory concentrations ($IC_{50}$) while directly accounting for background cell turnover rates.
Single-Cell Data Infrastructure
A specialized multi-omics data package containing single-cell profiling data tailored to explore ZEB1-dependent modulation of fibroblast polarization. This resource maps out the core molecular mechanics governing inflammation boundaries and immune checkpoint blockade sensitivity in colorectal cancer.
Early computational models and simulation frameworks:
Population Genetics Simulation
A computational framework designed for simulating base populations in honey bees (Apis mellifera) to support molecular genetic studies, mapping population structures, and evaluating breeding dynamics.
Quantitative Genetics & Composite Traits
Simulation workflows evaluating the accuracy of the unified approach in composite traits, heavily applied to modeling varroa-specific defense behaviors and genetic architectures in honey bees.